Chemical Carcinogens, Part 1

2-naphthylamine 3-methylcholanthrene 7,8-dihydrodiol Acad acid adducts adenomas alkylating agents aniline animals anthracene aromatic amines aromatic hydrocarbons assays bay-region dihydrodiol epoxide benzidine benzo[a]pyrene binding Biochem Biol Biophys bladder cancer bladder tumors Cancer Inst Cancer Res carcinogenesis carcinogenic carcinogenic activity carcinogenic potency carcinoma cause cells Chem Chem.-Biol chemical carcinogens chrysene compounds derivatives Dipple disease dose effects enantiomer enzymes epidemiological study ester evidence exposure guanine hamster hazard hepatomas human IARC incidence increased induced industrial Interact Jerina JNCI K-region laboratory leukemia lung lymphoma malignant mechanism metabolic metabolic activation metabolites methanesulfonate methyl methyl methanesulfonate mg/kg mice microsomal Miller mouse skin mustard mutagenic Mutat N-hydroxy-2-FAA N-hydroxylation naphthalene Natl Nature London nucleophiles occupational oxide papillomas Pharmacol phenanthrene polycyclic hydrocarbons Proc rat liver reaction reactive reported risk sarcomas Scheme Sims Table tissues toxic Toxicol tumors vitro vivo Weisburger wkly workers Yagi